2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N10403R
    4-Hydroxyestradiol (Standard)
    ABZ-amine (Standard) is the analytical standard of ABZ-amine. This product is intended for research and analytical applications. ABZ-amine (Amino albendazole) is an impurity of Albendazole. Albendazole is a member of the benzimidazole compounds used as a agent indicated for the treatment of a variety of worm infestations.
    4-Hydroxyestradiol (Standard)
  • HY-126852
    4-Hydroxy Atorvastatin lactone
    4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.
    4-Hydroxy Atorvastatin lactone
  • HY-W100784
    2,6-Dimethylphenylthiourea
    2,6-Dimethylphenylthiourea is a Xylazine metabolite. Xylazine is the first and most widely used α2-agonist.
    2,6-Dimethylphenylthiourea
  • HY-125446S
    2-Hydroxymethyl olanzapine-d3
    2-Hydroxymethyl olanzapine-d3 (LY-290411-d3) is a deuterium labeled 2-Hydroxymethyl olanzapine. 2-Hydroxymethyl olanzapine is a metabolite of Olanzapine..
    2-Hydroxymethyl olanzapine-d<sub>3</sub>
  • HY-131964R
    Imidacloprid-urea (Standard)
    Sodium ethylparaben (Standard) is the analytical standard of Sodium ethylparaben. This product is intended for research and analytical applications. Sodium ethylparaben (Sodium ethyl 4-hydroxybenzoate) acts as a water soluble antiseptic usually employed as safe for cosmetics.
    Imidacloprid-urea (Standard)
  • HY-12784AS
    Cycloguanil-d4 hydrochloride
    Cycloguanil-d4 (hydrochloride) is the deuterium labeled Cycloguanil hydrochloride. Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].
    Cycloguanil-d<sub>4</sub> hydrochloride
  • HY-133675S
    Mono(5-carboxy-2-ethylpentyl) phthalate-d4
    Mono(5-carboxy-2-ethylpentyl) phthalate-d4 (MECPP-d4) is a deuterium labeled Mono(5-carboxy-2-ethylpentyl) phthalate (HY-133675). Mono(5-carboxy-2-ethylpentyl) phthalate (MECPP) is a metabolite of Di-(2-ethylhexyl) phthalate (DEHP). Di(2-ethylhexyl) phthalate is the predominant plasticizer added to rigid polyvinyl chloride (PVC) to impart flexibility, temperature tolerance, optical clarity, strength and resistance to kinking.
    Mono(5-carboxy-2-ethylpentyl) phthalate-d<sub>4</sub>
  • HY-135387
    4-Desmethyl Istradefylline
    4-Desmethyl Istradefylline is a metabolite of Istradefylline. 4-Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
    4-Desmethyl Istradefylline
  • HY-W015788R
    1-Phenylethane-1,2-diol (Standard)
    1-Phenylethane-1,2-diol (Standard)
  • HY-W039924
    N-Azidoacetylmannosamine
    N-Azidoacetylmannosamine is an azide-labeled sugar that can be metabolically incorporated into glycoproteins. N-Azidoacetylmannosamine can then react with alkynes or phosphines that are linked to fluorescent or biotin tags for visualization or capture of the glycoproteins. N-Azidoacetylmannosamine can be used for studying glycan structures and functions in vivo.
    N-Azidoacetylmannosamine
  • HY-131466R
    N-Methyl Palbociclib (Standard)
    Hydroxyurea (Standard) is the analytical standard of Hydroxyurea. This product is intended for research and analytical applications. Hydroxyurea is a cell apoptosis inducer that inhibit DNA synthesis through inhibition of ribonucleotide reductase. Hydroxyurea shows anti-orthopoxvirus activity.
    N-Methyl Palbociclib (Standard)
  • HY-W700643
    Di-N-desethyl amiodarone hydrochloride
    Di-N-desethyl Amiodarone hydrochloride is a metabolite of Amiodarone (HY-14187). Di-N-desethyl Amiodarone hydrochloride is a strong inhibitor of the respiratory chain.
    Di-N-desethyl amiodarone hydrochloride
  • HY-129903
    N-Desethyl vardenafil
    N-Desethyl vardenafil is the major metabolite of Vardenafil (HY-B0442) and can be detected in human urine.
    N-Desethyl vardenafil
  • HY-W587960
    Hercynine
    Hercynine (Histidine-betaine) is an intermediate (precursor) and a redox metabolite of Ergothioneine (HY-N1914), which is found in the fine leaf algae, Schizosaccharomyces cerevisiae and honey bees. Hercynine has no effect on scavenging •OH radicals.
    Hercynine
  • HY-118614R
    β-Nicotyrine (Standard)
    β-Nicotyrine (Standard) is the analytical standard of β-Nicotyrine. This product is intended for research and analytical applications. β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid.
    β-Nicotyrine (Standard)
  • HY-121745
    Phosmet oxon
    Phosmet oxon (Imidoxon) is a main and toxic metabolite of phosmet. Phosmet is a cholinesterase inhibitor insecticide used on pome and stone fruits.
    Phosmet oxon
  • HY-138627B
    AST5902 mesylate
    AST5902 mesylate is a principal metabolite of Alflutinib, exhibiting significant antineoplastic activity. AST5902 mesylate contributes to the overall pharmacological effects in the treatment of non-small cell lung cancer. AST5902 mesylate is involved in the response to activating EGFR mutations and can help overcome EGFR T790M drug-resistant mutations.
    AST5902 mesylate
  • HY-131261
    Ibuprofen alcohol
    Ibuprofen alcohol, a nonsteroidal antiinflammatory agent (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs).
    Ibuprofen alcohol
  • HY-135910R
    3,4-Dehydro Cilostazol (Standard)
    3,4-Dehydro Cilostazol (Standard) is the analytical standard of 3,4-Dehydro Cilostazol. This product is intended for research and analytical applications. 3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study.
    3,4-Dehydro Cilostazol (Standard)
  • HY-W336012S
    Metoprolol EP impurity O-d7 hydrochloride
    Metoprolol EP impurity O-d7 (hydrochloride) is the deuterium labeled 3,3'-(Isopropylazanediyl)bis(1-(4-(2-methoxyethyl)phenoxy)propan-2-ol)[1].
    Metoprolol EP impurity O-d<sub>7</sub> hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity